Think about knowledgeable inflating a balloon with a small pump. No, we're not speaking a couple of clown at a celebration, however engineers in a laboratory designing a medical product to deal with weight problems.
Engineers on the Massachusetts Institute of Expertise (MIT) have designed a brand new sort of dynamic gastric balloon – a balloon that enters the abdomen – for weight reduction therapy. The design, detailed in a press launch dated December 3 study within the journal Machinemay be inflated on command and will provide an alternative choice to weight reduction medication and invasive procedures resembling gastric bypass.
A standard gastric balloon is actually a bag of air or salt water surgically inserted into the abdomen to offer the affected person a sense of fullness and forestall them from overeating. Though this has been proven to be efficient for short-term weight reduction, the abdomen has the irritating means to adapt to the brand new sensation, making the advantages non permanent, in line with the research. The brand new design from MIT engineers goals to keep away from this end result by inflating and deflating as wanted, with out ever permitting the abdomen to regulate.
“The essential idea is that we will have this dynamic balloon, so it might be inflated proper earlier than a meal and you then wouldn't be hungry. Then it might be deflated between meals,” stated Giovanni Traverso, who participated within the research and can be a gastroenterologist at Brigham and Girls's Hospital, a college. statement. Engineers examined this idea on pigs and located that the animals ate 60% much less when the gastric balloon was inflated earlier than their meals.
The MIT researchers positioned the machine into the pigs' stomachs by way of an incision within the stomach and managed its inflation with an exterior pump linked to the gastric balloon through a tube just like a feeding tube. Human sufferers may connect the exterior controller to their pores and skin.
“If folks, for instance, are unable to swallow, they obtain meals by way of a tube like this. We all know we will maintain the tubes for years. So there’s already precedent for different programs that may keep within the physique for a really very long time. This offers us some confidence within the long-term compatibility of this method,” Traverso defined. As a result of the current research was too quick to report weight reduction within the animals, the researchers at the moment are planning future long-term tasks.
“The deployment of conventional gastric balloons sometimes lasts six months or extra, and solely then will you see important weight reduction. We might want to consider our machine in the same or longer timeframe to show that it actually works higher,” stated Neil Zixun Jia of MIT, who led the research.
Initially, researchers created two prototypes for weight reduction options: the brand new gastric balloon and a four-armed machine that pushed in opposition to the abdomen wall. They in the end opted for the previous, reasoning that “the ball most likely distributed pressure higher” and “most likely was a safer strategy in the long term,” Traverso stated.
As Ozempic takes the world by storm, these engineers have designed a possible different for sufferers who, for varied causes, can not deal with weight problems with medicines or invasive surgical procedures resembling gastric bypass or stapling.
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